TRPC3 / interactors

Name: Short transient receptor potential channel 3 (TRPC3)
Official Symbol: TRPC3 provided by HGNC
Function:
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt) Nucleic Acids Res. 40: D71-D75 (2012).
Species External DB Questionmark c7dcdfe7852228a510704064c33a0706d8c0e915bceea718517e77f7950c2984
Entrez Gene UniprotKB DIP IntAct MINT BioGRID STRING IUPHAR-DB KEGG OMIM
Human
Seq 055e86e69a1b9fa3c345494da0168454ea5fcb72eb0f6a154a55bbbbbcb46d2f
7222External Q13507External DIP-34311NExternal Q13507External   113073External Q13507External 488External hsa:7222External 602345External
Mouse
Seq 055e86e69a1b9fa3c345494da0168454ea5fcb72eb0f6a154a55bbbbbcb46d2f
22065External Q9QZC1External       204329External Q9QZC1External   mmu:22065External  
Rat
Seq 055e86e69a1b9fa3c345494da0168454ea5fcb72eb0f6a154a55bbbbbcb46d2f
60395External Q9JMI9External DIP-59688NExternal     248816External Q9JMI9External   rno:60395External  
Biological Process:
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
Disease: No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 14-3-3 protein Ƣ/ơ Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 14-3-3 protein ƥ Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 14-3-3 protein Ƨ Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Aconitase Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ADT1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ALDOC Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Annexin 5 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 AP2A2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 AP2B1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 AQP-2 Inference Prediction 17699554
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ATP synthase Ƣ Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Basp1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 BKca Inference Prediction 19052171
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calmodulin Inference Prediction 11248050
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calreticulin Inference Prediction 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Caskin-1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 CaSR Inference Prediction 22778254
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Cav1.2 Inference Prediction 21672930
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Caveolin-1 Inference Prediction 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Citrate synthase Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Clathrin-H1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Cytochrome c oxidase 2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Cytochrome c oxidase 5A Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 DRP-2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Dynamin-1 heavy chain 1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Dynamin-1L Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Inference Prediction 18276585
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Ezrin Inference Prediction 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Fibronectin Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 FKBP12 Inference Prediction 15199065
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Fumarase Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 GC-A Inference Prediction 22027011
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 GLUD1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 GLUT-4 Inference Prediction 17156765
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Gơq Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Gơq/11 Inference Prediction 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Gz-ơ Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Homer-1 Inference Prediction 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Idh3B Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Inference Prediction 10518223
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R2 Inference Prediction 11290752
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Inference Prediction 10611319
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Junctate Inference Prediction 15302852
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Junctophilin-2 Inference Prediction 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 LETM1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MAP2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MDH1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MDH2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MG29 Inference Prediction 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MxA Inference Prediction 15757897
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Myosin-10 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCAM1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Inference Prediction 14736881
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Neurofascin Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Neuromodulin Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NKAơ1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NKAơ1 Inference Prediction 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NKAơ2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NKAơ3 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ơ-actinin Speculation Prediction 24146259
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai1 Inference Prediction 17360584
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai2 Inference Prediction 17360584
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai3 Inference Prediction 17360584
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ORP-150 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ơSNAP Yeast two-hybrid Human 1-341 Rat Brain cDNA library 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 p97/VCP Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PDE3A Inference Prediction 21799177
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PEBP1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PGK1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKA Inference Prediction 21799177
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKCƢ Inference Prediction 20179100
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKG1 Inference Prediction 14983059
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƢ1 Inference Prediction 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Inference Prediction 12437926
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ2 Inference Prediction 12970180
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƢ2 Inference Prediction 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƢ3 Inference Prediction 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PMCA Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PMCA Speculation Prediction 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PMCA2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PMCA3 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PMCA4 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Pyruvate kinase M1/M2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RACK1 Yeast two-hybrid Not specified 1-341 Human Embroynic kidney cDNA library 18755685
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RAP1A Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RAP1B Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RNF24 Inference Prediction 17850865
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RyR Inference Prediction 10983988
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RyR2 Inference Prediction 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SERCA2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SERCA2 Inference Prediction 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Slc1a2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Slc1a3 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SNAP23 Inference Prediction 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SNAP25 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SOD2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SRC Inference Prediction 16407161
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 STIM1 Speculation Prediction 22640869
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 STIM2 Speculation Prediction 22640869
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SV2A Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Synapsin1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Synaptotagmin 1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Syntaxin1a Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Syntaxin3 Inference Prediction 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Tenascin-R Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TrkB Inference Prediction 10677043
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Inference Prediction 9215637
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC4 Inference Prediction 16537542
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC5 Inference Prediction 12857742
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Inference Prediction 12032305
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC7 Inference Prediction 12032305
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPM4 Yeast two-hybrid Not used as a bait Human Brain cDNA library 18262493
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPP1 Inference Prediction 19812035
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 UCH-L1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAMP2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAMP2 Yeast two-hybrid Human 1-341 Rat Brain cDNA library 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAT2 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VDAC1 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VDAC3 Affinity purification-mass spectrometry Not used as a bait Rat Brain Crude membranes 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 WNK4 Inference Prediction 21670282
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vitro validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with recombinant proteins Reference
TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Expression system Species Region Expression system
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 BKca Fusion protein-pull down assay Not used Mouse podocyte lysates Chicken Full-length E. coli 19052171
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calmodulin Fusion protein-pull down assay Human 1-340 In vitro translation Not specified Full-length E. coli 12601176
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calmodulin Fusion protein-pull down assay Human 742-795 E. coli Rat Full-length In vitro translation 11248050
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 FKBP12 Co-immunoprecipitation Human Full-length Sf9 lysates Human Full-length Sf9 lysates 15199065
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Homer-1 Fusion protein-pull down assay Human Full-length HEK293 lysates Human Full-length E. coli 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Fusion protein-pull down assay Human 676-848 In vitro translation Human 638-926 E. coli 10611319
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Junctate Fusion protein-pull down assay Bovine Full-length HEK293 lysates Not specified 1-85 Not specified 15302852
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Junctophilin-2 Fusion protein-pull down assay Not used Rabbit back and leg fast-twich skeletal muscle lysates Mouse Full-length E. coli 19277847
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MxA Fusion protein-pull down assay Human 1-201 In vitro translation Human 572-662 E. coli 15757897
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Fusion protein-pull down assay Human 742-848 E. coli Not used HEK293 lysates 14736881
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Fusion protein-pull down assay Human 670-848 E. coli Not used Rat Cardiomyocyte lysates 17129578
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai1 Fusion protein-pull down assay Human 1-340 In vitro translation Human Full-length E. coli 17360584
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai1 Fusion protein-pull down assay Human 676-848 In vitro translation Human Full-length E. coli 17360584
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKCƢ Fusion protein-pull down assay Mouse 659-836 E. coli Not used DT40 lysates 20179100
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Yeast two-hybrid Human 1-340 Yeast Rat 750-1290 Yeast 12437926
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Yeast two-hybrid Human 1-171 Yeast Rat 796-920 Yeast 15744307
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RNF24 Fusion protein-pull down assay Not specified 1-201 In vitro translation Human 98-148 E. coli 17850865
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SRC Fusion protein-pull down assay Mouse 1-340 In vitro translation Chicken Full-length E. coli 16407161
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Fusion protein-pull down assay Not specified Full-length HEK293 lysates Not specified 1-347 E. coli 15834157
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Fusion protein-pull down assay Human 38-381 E. coli Not used Rabbit fast switch muscle lysates 24613381
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Yeast two-hybrid Not specified 642-842 Yeast Not specified 642-842 Yeast 15834157
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPM4 Yeast two-hybrid Human Full-length Yeast Human Full-length Yeast 18262493
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ADT1 Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 AQP-2 Co-immunofluorescence staining Rat kidney medullary collecting duct 20107112
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 AQP-2 Co-immunofluorescence staining Rat kidney duct section 17699554
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 AQP-2 Co-immunoprecipitation mIMCD-3 17699554
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 AQP-2 Co-immunoprecipitation Rat medulla lysates 17699554
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 BKca Co-immunofluorescence staining HEK293T Not specified Full-length Not specified Full-length 19052171
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 BKca Co-immunoprecipitation Mouse podocyte lysates 19052171
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 BKca Co-immunoprecipitation HEK293T Not specified Full-length Not specified Full-length 19052171
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calmodulin Co-immunoprecipitation Mouse skeletal myotube lysates 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calreticulin Co-immunoprecipitation Mouse skeletal myotube lysates 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 CaSR Co-immunofluorescence staining Mouse submandibular gland (SMG) ductal tissue section 22778254
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 CaSR Co-immunoprecipitation Mouse submandibular gland (SMG) ductal cell lysates 22778254
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Cav1.2 Co-immunoprecipitation Chick embryonic heart lysates 21672930
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Caveolin-1 Co-immunofluorescence staining HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Caveolin-1 Co-immunoprecipitation HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Clathrin-H1 Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 DRP-2 Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Dynamin-1 heavy chain 1 Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Co-immunofluorescence staining HEK293T Human Full-length Human Full-length 19074769
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Co-immunoprecipitation HEK293T Human Full-length Human Full-length 21757714
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Co-immunoprecipitation HEK293T Human Full-length Human Full-length 18276585
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Co-immunoprecipitation HEK293T Human Full-length Human Full-length 19074769
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Co-immunoprecipitation TF-1 19074769
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Ezrin Co-immunoprecipitation HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 FKBP12 Co-immunoprecipitation Rat cerebral cortex 15199065
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 GC-A Co-immunoprecipitation HEK293 Not specified Full-length Rat Full-length 22027011
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 GC-A Co-immunoprecipitation Mouse cardiac myocyte lysates Not used Rat Full-length 22027011
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 GC-A Fluorescence resonance energy transfer HEK293 Not specified Full-length Rat Full-length 22027011
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 GLUT-4 Co-immunoprecipitation Mouse cardiomyocytes 17156765
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Gơq/11 Co-immunoprecipitation HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Gơq/11 Co-immunoprecipitation MDCK Not specified Full-length Not used 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Gz-ơ Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Homer Co-immunoprecipitation Mouse skeletal myotube lysates 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Co-immunoprecipitation HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Co-immunoprecipitation Rat cerebral arterial lysates 20378853
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Co-immunoprecipitation Rat mesenteric artery lysates 23045459
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Co-immunoprecipitation HEK293 Human Full-length Rat Full-length 10518223
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Co-immunoprecipitation MDCK Not specified Full-length Not used 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Co-immunoprecipitation HEK293 20022948
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R2 Co-immunoprecipitation HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R2 Co-immunoprecipitation Sheep uterine arterial endothelial cell 16899571
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunofluorescence staining HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunofluorescence staining Mouse pancreatic acini 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunofluorescence staining Mouse parotid acini 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunofluorescence staining Mouse submandibular gland duct 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation HEK293 Human Full-length Not used 14505576
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation Mouse brain tissue 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation Mouse pancreatic tissue 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation Mouse submandibular gland lysates 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation HEK293T Human Full-length Human Full-length 10611319
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation MDCK Not specified Full-length Not used 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation HEK293 Human Full-length Not used 10983988
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Junctophilin-2 Co-immunoprecipitation Mouse skeletal muscle myoblast lysates Not used Mouse Full-length 20095964
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Junctophilin-2 Co-immunoprecipitation Mouse skeletal myotube lysates 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MG29 Co-immunoprecipitation Mouse skeletal myotube lysates 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MxA Co-immunoprecipitation HEK293T Human Full-length Human Full-length 15757897
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Co-immunofluorescence staining Rat myocyte section 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Co-immunofluorescence staining Rat cardiomyocytes 17129578
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Co-immunofluorescence staining dnTRPC3 TG mouse heart myocyte 20351294
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Co-immunoprecipitation HEK293 Human Full-length Not used 14736881
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Co-immunoprecipitation Sf9 Mouse Not specified Rat Not specified 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Co-immunoprecipitation Rat ventricle lysates 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Co-immunoprecipitation Rat cardiomyocytes 17129578
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Neuromodulin Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NKAơ1 Co-immunofluorescence staining Rat myocyte section 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NKAơ1 Co-immunoprecipitation Rat ventricle lysates 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NKAơ1 Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ơ-actinin Co-immunofluorescence staining Rat ventricular myocytes 24146259
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai1 Co-immunoprecipitation COS-7 Human Full-length Human Full-length 17360584
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai1 Co-immunoprecipitation HEK293 20022948
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai2 Co-immunoprecipitation Human platelets 22640869
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai2 Co-immunoprecipitation COS-7 Human Full-length Human Full-length 17360584
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai3 Co-immunoprecipitation Human platelets 22640869
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai3 Co-immunoprecipitation COS-7 Human Full-length Human Full-length 17360584
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ơSNAP Co-immunofluorescence staining Rat hippocampal neuron 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ơSNAP Co-immunofluorescence staining HSG cell 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ơSNAP Co-immunofluorescence staining HEK293 Human Full-length Not used 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 ơSNAP Co-immunoprecipitation HEK293 Human Full-length Not used 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PDE3A Co-immunoprecipitation HEK293 Not specified Full-length Not used 21799177
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKA Co-immunoprecipitation HEK293 Not specified Full-length Not used 21799177
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKCƢ Co-immunoprecipitation DT40 20179100
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Co-immunoprecipitation HEK293 Mouse Full-length Human Full-length 19289841
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƢ1 Co-immunoprecipitation HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Co-immunoprecipitation HEK293T Human Full-length Rat Full-length 21757714
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Co-immunoprecipitation Human erythroid cell 18276585
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Co-immunoprecipitation HEK293T Human Full-length Rat Full-length 18276585
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Co-immunoprecipitation HEK293T Human Full-length Rat Full-length 12437926
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƢ1 Co-immunoprecipitation MDCK Not specified Full-length Not used 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Co-immunoprecipitation HEK293T Human Full-length Rat Full-length 19074769
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ2 Co-immunoprecipitation HEK293 Mouse Full-length Chicken Full-length 12970180
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ2 Co-immunoprecipitation HEK293 Mouse Full-length Rat Full-length 19289841
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƢ2 Co-immunoprecipitation MDCK Not specified Full-length Not used 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ2 Co-immunoprecipitation HEK293 Mouse Full-length Chicken Full-length 20179100
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƢ3 Co-immunoprecipitation MDCK Not specified Full-length Not used 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PMCA Co-immunoprecipitation Mouse brain tissue 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PMCA Co-immunoprecipitation Mouse pancreatic tissue 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PMCA Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RACK1 Co-immunofluorescence staining HEK293 Not specified Full-length Not used 18755685
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RACK1 Co-immunoprecipitation HEK293 Not specified Full-length Not used 18755685
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RACK1 Co-immunoprecipitation Rat brain lysates 18755685
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RNF24 Co-immunofluorescence staining HEK293 Not specified Full-length Human Full-length 17850865
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RyR Co-immunoprecipitation HEK293 Human Full-length Not used 10983988
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RyR2 Co-immunofluorescence staining Rat myocyte section 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RyR2 Co-immunoprecipitation Rat ventricle lysates 17012351
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SERCA2 Co-immunoprecipitation HEK293 Human Full-length Not used 11524429
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SERCA2 Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SNAP23 Co-immunofluorescence staining Rat hippocampal neuron 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SNAP23 Co-immunofluorescence staining HEK293 Human Full-length Not used 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SNAP23 Co-immunoprecipitation HEK293 Human Full-length Not used 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SRC Co-immunoprecipitation COS-7 Mouse Full-length Chicken Full-length 16407161
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 STIM1 Co-immunoprecipitation Human platelets 22640869
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 STIM1 Co-immunoprecipitation HEK293 Human Full-length Human Full-length 23068106
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 STIM1 Co-immunoprecipitation Not specified Full-length (mutant) Human Full-length 24464579
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 STIM2 Co-immunoprecipitation Human platelets 22640869
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Synaptotagmin 1 Co-immunoprecipitation Rat brain lysates 18205297
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Syntaxin3 Co-immunofluorescence staining Rat hippocampal neuron 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Syntaxin3 Co-immunofluorescence staining HEK293 Human Full-length Not used 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Syntaxin3 Co-immunoprecipitation Rat hippocampal neuron 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Syntaxin3 Co-immunoprecipitation HEK293 Human Full-length Not used 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Syntaxin3 Co-immunoprecipitation MDCK Not specified Full-length Not used 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TrkB Co-immunofluorescence staining Rat brain pontine neuron 10677043
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TrkB Co-immunoprecipitation Rat brain lysates 10677043
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation HSY cell 15834157
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation Human platelets 19260825
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation HEK293 15972814
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation Rat carotid artery smooth muscle cell 19502552
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation Mouse skeletal myotube lysates 18215135
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation Mouse primary skeletal myotubes 24613381
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation HEK293T Human Full-length Human Full-length 9215637
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation C2C12 21996795
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation HEK293 Human Full-length Human Full-length 17486119
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Co-immunoprecipitation Rat brain microsome 12857742
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC4 Co-immunofluorescence staining Porcine primary aortic endothelial cell 16537542
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC4 Co-immunoprecipitation Rat brain microsome 12857742
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC4 Co-immunoprecipitation HEK293 Human Full-length Mouse Full-length 16537542
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC4 Co-immunoprecipitation Porcine primary aortic endothelial cell 16537542
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC4 Co-immunoprecipitation TRPC3 dnTRPC4 DTG mouse heart lysataes 20351294
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC5 Co-immunoprecipitation Rat brain microsome 12857742
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunofluorescence staining MDA-MB-231 19689790
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation dnTRPC6 Neonatal rat ventricular myocytes 20351294
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation Human platelets 19260825
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation MDA-MB-231 19689790
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation HEK293 Human Full-length Human Full-length 12032305
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation Rat brain synaptome 12377790
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation Sf9 Human Full-length Mouse Full-length 12377790
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation Human platelets 16270640
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation MDCK Not specified Full-length Not used 15623527
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation HEK293T Human Full-length Human Full-length 19074769
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Co-immunoprecipitation TF-1 19074769
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC6 Fluorescence resonance energy transfer HEK293 Human Full-length Human Full-length 12032305
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC7 Co-immunoprecipitation Sf9 Human Full-length Mouse Full-length 12377790
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC7 Co-immunoprecipitation Rat brain synaptome 12377790
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC7 Co-immunoprecipitation Rat ventricular myocytes 18502908
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC7 Co-immunoprecipitation CHO Human Full-length Mouse 1-494 15537648
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC7 Fluorescence resonance energy transfer HEK293 Human Full-length Mouse Full-length 12032305
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPM4 Co-immunofluorescence staining HEK293T Human Full-length Human Full-length 18262493
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPM4 Co-immunoprecipitation HEK293T Human Full-length Human Full-length 18262493
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPP1 Co-immunofluorescence staining LLC-PK1 Not used Human 1-697 19812035
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPP1 Co-immunoprecipitation HEK293 Mouse Full-length Human 1-697 19812035
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAMP2 Co-immunofluorescence staining Rat hippocampal neuron 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAMP2 Co-immunofluorescence staining HSG cell 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAMP2 Co-immunofluorescence staining HEK293 Human Full-length Not used 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAMP2 Co-immunoprecipitation Rat hippocampal neuron 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAMP2 Co-immunoprecipitation HEK293 Human Full-length Not used 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 WNK4 Co-immunoprecipitation Rat aorta lysates 21670282
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 WNK4 Co-immunoprecipitation HEK293T Human Full-length Mouse Full-length 21670282
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calmodulin Fluorescence probe labeling Human 764-793 Bovine Not determined 100 nM 11248050
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calmodulin Fluorescence probe labeling Human 764-793 Not specified Not determined 100 nM 11290752
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calmodulin Fusion protein-pull down assay Human 761-795 Not specified Not determined 11290752
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Co-immunoprecipitation Human 671-746 Human Not determined 19074769
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Co-immunoprecipitation Human Not determined Rat IP3 binding domain 10518223
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Fusion protein-pull down assay Mouse 725-848 Not specified 654-688 11290752
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R2 Fusion protein-pull down assay Mouse 725-848 Not specified 675-695 11290752
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Co-immunoprecipitation Human 775-787 Rat Not determined 18276585
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Fusion protein-pull down assay Human 777-797 Human 669-698 10611319
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Fusion protein-pull down assay Human 777-797 Human 751-821 10611319
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Fusion protein-pull down assay Human 761-795 Human 669-698 11248050
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Fusion protein-pull down assay Human 761-795 Human 669-698 11290752
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Fusion protein-pull down assay Mouse 725-848 Human 681-698 11290752
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Junctophilin-2 Fusion protein-pull down assay Mouse Not determined Mouse 143-234 19277847
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 MxA Fusion protein-pull down assay Human 1-201 Human 572-662 15757897
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 NCX1 Fusion protein-pull down assay Human 670-848 Rat Not determined 17129578
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKCƢ Fusion protein-pull down assay Mouse 659-836 Chicken Not determined 20179100
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Fusion protein-pull down assay Human 1-52 Rat 794-933 16500902
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Fusion protein-pull down assay Human 40-48 Rat 861-920 15744307
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Yeast two-hybrid Human 1-340 Rat 780-920 12437926
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Yeast two-hybrid Human 40-46 Rat 861-920 15744307
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ2 Co-immunoprecipitation Mouse Not determined Chicken 810-829 12970180
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RACK1 Yeast two-hybrid Not specified 221-342 Human Not determined 18755685
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SRC Co-immunoprecipitation Mouse 1-370 Chicken SH2 domain 16407161
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Yeast two-hybrid Not specified 1-341 Not specified 1-73 15834157
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPM4 Co-immunoprecipitation Human Not determined Human 858-1188 18262493
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPP1 Fusion protein-pull down assay Mouse 659-753 Human 1-697 19812035
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 VAMP2 Yeast two-hybrid Human 1-123 Rat Not determined 15327778
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 WNK4 Co-immunoprecipitation Human 1-196 Mouse 441-799 21670282
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 WNK4 Co-immunoprecipitation Human 1-196 Mouse 441-1032 21670282
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Calmodulin Patch clamp Inhibition 11248050
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 CaSR Cell surface biotinylation Increase in plasma membrane level 22778254
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Calcium measurement Activation 18276585
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Epo-R Patch clamp Activation 18276585
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Homer-1 Cell surface biotinylation Increase in plasma membrane level 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Homer-1 Patch clamp Activation 16887806
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Calcium measurement Activation 10518223
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R1 Patch clamp Activation 10518223
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Calcium measurement Activation 10611319
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Calcium measurement Inhibition 10611319
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 IP3R3 Patch clamp Activation 11248050
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Junctate Patch clamp Activation 15302852
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 Orai1 Patch clamp Activation 18287061
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKG1 In vitro PTM assay Phosphorylation (Tyr-11) 14983059
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PKG1 In vitro PTM assay Phosphorylation (Ser-263) 14983059
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Calcium measurement Activation 12437926
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ1 Calcium measurement Activation 15744307
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ2 Calcium measurement Activation 12970180
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 PLCƣ2 Patch clamp Activation 12970180
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RNF24 Cell surface biotinylation Decrease in plasma membrane level 17850865
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 RyR Patch clamp Activation 10983988
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SRC Calcium measurement Activation 16407161
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 SRC In vivo PTM assay Phosphorylation (Tyr-226) 16407161
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPC1 Patch clamp New channel creation 10882720
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPM4 Patch clamp Inhibition 18262493
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 TRPP1 Calcium measurement Activation 19812035
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 WNK4 Cell surface biotinylation Decrease in plasma membrane level 21670282
TRPC3 Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4 WNK4 Ion influx measurement Inhibition 21670282
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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