Ribophorin II / TRP channels
Name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
(Ribophorin II)
Official Symbol: RPN2
provided by HGNC
Function:
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species |
External DB
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Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
![]() |
6185![]() |
P04844![]() |
DIP-38153N![]() |
P04844![]() |
MINT-8247596![]() |
112100![]() |
P04844![]() |
hsa:6185![]() |
180490![]() |
|
Mouse
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20014![]() |
Q9DBG6![]() |
DIP-32105N![]() |
Q9DBG6![]() |
MINT-1859656![]() |
202990![]() |
Q9DBG6![]() |
mmu:20014![]() |
||
Rat
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64701![]() |
P25235![]() |
DIP-37304N![]() |
P25235![]() |
MINT-4996562![]() |
249196![]() |
P25235![]() |
rno:64701![]() |
PPI pairs:
Biological Process:
- GO:0043687
: post-translational protein modification
- GO:0018279
: protein N-linked glycosylation via asparagine
- GO:0006614
: SRP-dependent cotranslational protein targeting to membrane
- GO:0006412
: translation
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
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Screening
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Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPP1 |
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Ribophorin II | Affinity purification-mass spectrometry | Mouse | Not specified | Mouse | Vascular smooth muscle | MOVAS lysates | 19879844 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
