HOP/STI1 / TRP channels
Name: Stress-induced-phosphoprotein 1
(HOP/STI1)
Official Symbol: STIP1
provided by HGNC
Function:
Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species |
External DB
![]() |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
![]() |
10963![]() |
P31948![]() |
DIP-41085N![]() |
P31948![]() |
MINT-132047![]() |
116162![]() |
P31948![]() |
hsa:10963![]() |
605063![]() |
|
Mouse
![]() |
20867![]() |
Q60864![]() |
DIP-34124N![]() |
Q60864![]() |
MINT-1869468![]() |
203539![]() |
Q60864![]() |
mmu:20867![]() |
||
Rat
![]() |
192277![]() |
O35814![]() |
DIP-57359N![]() |
MINT-4576943![]() |
251401![]() |
O35814![]() |
rno:192277![]() |
PPI pairs:
Biological Process:
- GO:0007411
: axon guidance
- GO:0006950
: response to stress
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
![]() ![]() ![]() ![]() ![]() |
![]() |
Screening
![]() |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPML1 |
![]() |
HOP/STI1 | Inference | Prediction | 19117012 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

![]() ![]() ![]() ![]() ![]() |
![]() |
Validation: In vivo validation
![]() |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Assay with endogenous proteins | Assay with overexpressed proteins | Reference | ||||||||
Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | |||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | ||||
TRPML1 |
![]() |
HOP/STI1 | Co-immunoprecipitation | CHO | Human | Full-length | Not used | 19117012 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
