TRPV5 / Klotho

Interaction: TRPV5Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / KlothoDetail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPV5 Klotho Inference Prediction 16239475
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPV5 Klotho Co-immunofluorescence staining Mouse kidney section 16239475
TRPV5 Klotho Co-immunoprecipitation mIMCD-3 Human Full-length Mouse Full-length 23747339
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPV5 Klotho Calcium measurement Activation 16239475
TRPV5 Klotho Calcium measurement Activation 18495742
TRPV5 Klotho Cell surface biotinylation Increase in plasma membrane level 16239475
TRPV5 Klotho Cell surface biotinylation Increase in plasma membrane level 18606998
TRPV5 Klotho In vitro PTM assay Glycosylation (Asn-358) 16239475
TRPV5 Klotho Patch clamp Activation 16239475
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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