TRPV5 / Calmodulin

Interaction: TRPV5Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / CalmodulinDetail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPV5 Calmodulin Inference Prediction 15123711
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vitro validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with recombinant proteins Reference
TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Expression system Species Region Expression system
TRPV5 Calmodulin Fusion protein-pull down assay Mouse Full-length In vitro translation Not specified Full-length Not specified 15123711
TRPV5 Calmodulin Fusion protein-pull down assay Mouse 1-327 In vitro translation Not specified Full-length Not specified 15123711
TRPV5 Calmodulin Fusion protein-pull down assay Mouse 578-730 In vitro translation Not specified Full-length Not specified 15123711
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPV5 Calmodulin Fluorescence probe labeling Human 587-616 Not specified Not determined 306 nM 20686800
TRPV5 Calmodulin Fusion protein-pull down assay Human ARD domain Not specified Not determined 20926660
TRPV5 Calmodulin Fusion protein-pull down assay Human 696-729 Not specified Not determined 21576356
TRPV5 Calmodulin Native-gel electrophoresis Human 696-729 Not specified Not determined 21576356
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPV5 Calmodulin Calcium measurement Inhibition 21576356
TRPV5 Calmodulin Patch clamp Inhibition 21576356
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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