TRPV2 / SYNE1
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Screening
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Experimental screening | Non-experimental screening | Reference | |||||||
TRP channel construct | Interactor source | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
TRPV2 | SYNE1 | Yeast two-hybrid | Mouse | 1-167 | Human | Heart | cDNA library | 16875688 |
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Validation: In vitro validation
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Assay with recombinant proteins | Reference | ||||||||
TRP channel construct | Interactor construct | ||||||||
TRP channel | Interactor | Method | Species | Region | Expression system | Species | Region | Expression system | |
TRPV2 | SYNE1 | Fusion protein-pull down assay | Not used | Rat heart lysates | Human | 1-476 (in GSRP-56 Variant) | E. coli | 16875688 |
(
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Characterization
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Binding region mapping | Stoichiometry | Affinity (Kd) | Reference | ||||||
TRP channel | Interactor | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | |||
TRPV2 | SYNE1 | Fusion protein-pull down assay | Rat | Not determined | Human | 1-258 (in GSRP-56 Variant) | 16875688 | ||
TRPV2 | SYNE1 | Fusion protein-pull down assay | Rat | Not determined | Human | 1-258 | 16875688 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
