TRPV1 / Src

Interaction: TRPV1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / SrcDetail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPV1 SRC Inference Prediction 15084474
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPV1 SRC Co-immunoprecipitation Rat dorsal root ganglion neuron 15084474
TRPV1 SRC Co-immunoprecipitation HEK293 16319926
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPV1 SRC Fusion protein-pull down assay Human 1-433 Rat 83-144 16319926
TRPV1 SRC Fusion protein-pull down assay Human 681-839 Rat 83-144 16319926
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPV1 SRC Calcium measurement Activation 16319926
TRPV1 SRC In vitro PTM assay Phosphorylayion (Tyr-200) 16319926
TRPV1 SRC In vivo PTM assay Phosphorylation 15084474
TRPV1 SRC In vivo PTM assay Phosphorylayion (Tyr-200) 16319926
TRPV1 SRC Patch clamp Activation 15084474
TRPV1 SRC Patch clamp Activation 16319926
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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