TRPV1 / KvƢ2
Interaction:
TRPV1
/
KvƢ2
/
KvƢ2
 Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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Screening
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| Experimental screening | Non-experimental screening | Reference | |||||||
| TRP channel construct | Interactor source | ||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
| TRPV1 | KvƢ2 | Affinity purification-mass spectrometry | Not used | Mouse | Dorsal root ganglion tissue | Lysates | 24036102 | ||
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Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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| Validation: In vivo validation
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| Assay with endogenous proteins | Assay with overexpressed proteins | Reference | |||||||
| Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | ||||||
| TRP channel | Interactor | Method | Species | Region | Species | Region | |||
| TRPV1 | KvƢ2 | Co-immunofluorescence staining | Mouse dorsal root ganglion neuron | 24036102 | |||||
| TRPV1 | KvƢ2 | Co-immunofluorescence staining | HEK293 tsA 201 | Mouse | Full-length | Not specified | Not specified | 24036102 | |
| TRPV1 | KvƢ2 | Co-immunoprecipitation | HEK293 tsA 201 | Mouse | Full-length | Not specified | Not specified | 24036102 | |
(:
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|
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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| Functional consequence
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| TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
| TRPV1 | KvƢ2 | Cell surface biotinylation | Increase in plasma membrane level | 24036102 | |||||||
(:
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