TRPP1 / Tropomyosin 1

Interaction: TRPP1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / Tropomyosin 1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPP1 Tropomyosin 1 Yeast two-hybrid Human 682-968 Human Heart cDNA library 12527301
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vitro validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with recombinant proteins Reference
TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Expression system Species Region Expression system
TRPP1 Tropomyosin 1 Fusion protein-pull down assay Human 682-968 E. coli Human Full-length E. coli 12527301
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPP1 Tropomyosin 1 Co-immunofluorescence staining NIH-3T3 Human Full-length Human Full-length 12527301
TRPP1 Tropomyosin 1 Co-immunoprecipitation NIH-3T3 Human Full-length Human Full-length 12527301
TRPP1 Tropomyosin 1 Co-immunoprecipitation Xenopus oocyte Human Full-length Human Full-length 12527301
TRPP1 Tropomyosin 1 Co-immunoprecipitation HEK293 12527301
TRPP1 Tropomyosin 1 Co-immunoprecipitation Human kidney tissue 12527301
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPP1 Tropomyosin 1 Yeast two-hybrid Human 821-878 Human 152-196 12527301
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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