TRPP1 / TRPV4

Interaction: TRPP1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / TRPV4Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPP1 TRPV4 Inference Prediction 18695040
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPP1 TRPV4 Co-immunofluorescence staining MDCK 18695040
TRPP1 TRPV4 Co-immunofluorescence staining Mouse orpk collecting duct cell line 23977387
TRPP1 TRPV4 Co-immunoprecipitation HEK293 tsA 201 Human Full-length Mouse Full-length 20682256
TRPP1 TRPV4 Co-immunoprecipitation Rat mesenteric artery endothelial cell Human Full-length Mouse Full-length 25114176
TRPP1 TRPV4 Co-immunoprecipitation HEK293 Human Full-length Mouse Full-length 25114176
TRPP1 TRPV4 Co-immunoprecipitation HEK293 Human C-terminus Mouse C-terminus 18695040
TRPP1 TRPV4 Co-immunoprecipitation Mouse inner medullary collecting duct cell 23977387
TRPP1 TRPV4 Co-immunoprecipitation Mouse orpk collecting duct cell line 23977387
TRPP1 TRPV4 Fluorescence resonance energy transfer HEK293 Human Full-length Mouse Full-length 25114176
TRPP1 TRPV4 Fluorescence resonance energy transfer HEK293 Human Full-length Mouse Full-length 18695040
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPP1 TRPV4 Atomic force microscopy(AFM) analysis 2:2 20682256
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPP1 TRPV4 Patch clamp New channel creation 25114176
TRPP1 TRPV4 Patch clamp New channel creation 18695040
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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