TRPML3 / TRPML1

Interaction: TRPML3Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / TRPML1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPML3 TRPML1 Inference Prediction 16606612
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPML3 TRPML1 Co-immunofluorescence staining HEK293 19557826
TRPML3 TRPML1 Co-immunofluorescence staining CHO Human Full-length Human Full-length 19885840
TRPML3 TRPML1 Co-immunoprecipitation HEK293 Human Full-length Not specified Full-length 19522758
TRPML3 TRPML1 Co-immunoprecipitation HEK293 19557826
TRPML3 TRPML1 Co-immunoprecipitation CHO Human Full-length Human Full-length 19885840
TRPML3 TRPML1 Co-immunoprecipitation HEK293 Human Full-length (mutation in the pore region) Human Full-length (mutation in the pore region) 20736310
TRPML3 TRPML1 Fluorescence resonance energy transfer HEK293 Not specified Full-length Not specified Full-length 23469151
TRPML3 TRPML1 Fluorescence resonance energy transfer HEK293 Mouse Full-length Human Full-length 16606612
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPML3 TRPML1 Co-immunofluorescence staining Increase in lysosomal membrane level 16606612
TRPML3 TRPML1 Patch clamp New channel creation 19885840
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

To prevent spam comments, we use reCAPTCHA. Please type correct words into the following box.