TRPML1 / LAPTM4b
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Screening
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Experimental screening | Non-experimental screening | Reference | |||||||
TRP channel construct | Interactor source | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
TRPML1 | LAPTM4b | Yeast two-hybrid | Human | Full-length | Human | adult brain | cDNA library | 21224396 |
(
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Validation: In vitro validation
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Assay with recombinant proteins | Reference | ||||||||
TRP channel construct | Interactor construct | ||||||||
TRP channel | Interactor | Method | Species | Region | Expression system | Species | Region | Expression system | |
TRPML1 | LAPTM4b | Yeast two-hybrid | Human | Full-length | Yeast | Human | 79-141 | Yeast | 21224396 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Validation: In vivo validation
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Assay with endogenous proteins | Assay with overexpressed proteins | Reference | |||||||
Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | ||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | |||
TRPML1 | LAPTM4b | Co-immunofluorescence staining | ARPE-19 | Human | Full-length | Human | Full-length | 21224396 | |
TRPML1 | LAPTM4b | Co-immunoprecipitation | HeLa | Human | Full-length | Human | Full-length | 21224396 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
