TRPM7 / RACK1
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Screening
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Experimental screening | Non-experimental screening | Reference | |||||||
TRP channel construct | Interactor source | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
TRPM7 | RacK1 | Inference | Prediction | 18258429 |
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:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Validation: In vitro validation
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Assay with recombinant proteins | Reference | ||||||||
TRP channel construct | Interactor construct | ||||||||
TRP channel | Interactor | Method | Species | Region | Expression system | Species | Region | Expression system | |
TRPM7 | RacK1 | Fusion protein-pull down assay | Mouse | ơ-kinase domain | E. coli | Mouse | Full-length | In vitro translation | 18258429 |
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Characterization
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Binding region mapping | Stoichiometry | Affinity (Kd) | Reference | ||||||
TRP channel | Interactor | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | |||
TRPM7 | RacK1 | Fusion protein-pull down assay | Mouse | ơ-kinase domain | Mouse | Not determined | 18258429 |
(
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Functional consequence
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TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
TRPM7 | RacK1 | Patch clamp | Inhibition | 18258429 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
