TRPM7 / PLCƣ1

Interaction: TRPM7Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / PLCƣ1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPM7 PLCƣ1 Inference Prediction 11941371
TRPM7 PLCƢ1 Yeast two-hybrid Not used as a bait Rat Brain cDNA library 11161216
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vitro validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with recombinant proteins Reference
TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Expression system Species Region Expression system
TRPM7 PLCƢ1 Fusion protein-pull down assay Rat 1352-1862 E. coli Rat Full-length HEK293T lysates 11941371
TRPM7 PLCƢ1 Fusion protein-pull down assay Not specified Kinase domain E. coli Not specified Full-length HEK293 lysates 22180838
TRPM7 PLCƢ1 Yeast two-hybrid Rat 1532-1862 Yeast Rat 643-1216 Yeast 11941371
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPM7 PLCƢ1 Yeast two-hybrid Rat 1532-1862 Rat 643-797 11941371
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPM7 PLCƢ1 Patch clamp Inhibition 11941371
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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