TRPM6 / TRPM7
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Screening
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Experimental screening | Non-experimental screening | Reference | |||||||
TRP channel construct | Interactor source | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
TRPM6 | TRPM7 | Inference | Prediction | 14976260 |
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Validation: In vivo validation
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Assay with endogenous proteins | Assay with overexpressed proteins | Reference | |||||||
Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | ||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | |||
TRPM6 | TRPM7 | Fluorescence resonance energy transfer | HEK293 | Human | Full-length | Mouse | Full-length | 14976260 |
(
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Characterization
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Binding region mapping | Stoichiometry | Affinity (Kd) | Reference | ||||||
TRP channel | Interactor | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | |||
TRPM6 | TRPM7 | Fusion protein-pull down assay | Mouse | 1711-2028 | Mouse | 1548-1863 | 19228120 |
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Functional consequence
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TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
TRPM6 | TRPM7 | Patch clamp | Activation | 14976260 | |||||||
TRPM6 | TRPM7 | Patch clamp | New channel creation | 24385424 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
