TRPM4 / Calmodulin
Interaction:
TRPM4
/
Calmodulin
/
Calmodulin
 Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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Screening
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| Experimental screening | Non-experimental screening | Reference | |||||||
| TRP channel construct | Interactor source | ||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
| TRPM4 | Calmodulin | Inference | Prediction | 15590641 | |||||
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:
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|
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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| Characterization
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| Binding region mapping | Stoichiometry | Affinity (Kd) | Reference | ||||||
| TRP channel | Interactor | ||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Region | |||
| TRPM4 | Calmodulin | Fusion protein-pull down assay | Human | 5-25 | Not specified | Not determined | 15590641 | ||
| TRPM4 | Calmodulin | Fusion protein-pull down assay | Human | 186-212 | Not specified | Not determined | 15590641 | ||
| TRPM4 | Calmodulin | Fusion protein-pull down assay | Human | 1076-1098 | Not specified | Not determined | 15590641 | ||
| TRPM4 | Calmodulin | Fusion protein-pull down assay | Human | 1146-1167 | Not specified | Not determined | 15590641 | ||
| TRPM4 | Calmodulin | Fusion protein-pull down assay | Human | 1095-1151 | Not specified | Not determined | 15590641 | ||
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
|
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
|
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|
| Functional consequence
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| TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
| TRPM4 | Calmodulin | Patch clamp | Activation | 15590641 | |||||||
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)