TRPC4 / PLCƣ1

Interaction: TRPC4Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / PLCƣ1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPC4 PLCƣ1 Inference Prediction 12437926
TRPC4 PLCƢ1 Inference Prediction 10980202
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vitro validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with recombinant proteins Reference
TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Expression system Species Region Expression system
TRPC4 PLCƣ1 Yeast two-hybrid Human 1-330 Yeast Rat 750-1290 Yeast 12437926
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPC4 PLCƢ1 Co-immunofluorescence staining Neonatal rat ventricular myocytes Not used Mouse Full-length 25049082
TRPC4 PLCƢ1 Co-immunoprecipitation Neonatal rat ventricular myocytes Human Full-length Mouse Full-length 25049082
TRPC4 PLCƢ1 Co-immunoprecipitation HEK293 Mouse Full-length Not used 10980202
TRPC4 PLCƢ1 Co-immunoprecipitation Mouse brain tissue 10980202
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPC4 PLCƣ1 Yeast two-hybrid Human 1-330 Rat 780-920 12437926
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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