TRPC4 / IP3R2
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Screening
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Experimental screening | Non-experimental screening | Reference | |||||||
TRP channel construct | Interactor source | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
TRPC4 | IP3R2 | Inference | Prediction | 11163362 |
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Validation: In vitro validation
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Assay with recombinant proteins | Reference | ||||||||
TRP channel construct | Interactor construct | ||||||||
TRP channel | Interactor | Method | Species | Region | Expression system | Species | Region | Expression system | |
TRPC4 | IP3R2 | Fusion protein-pull down assay | Human | Full-length | HEK293 lysates | Rat | 2544-2701 | E. coli | 11163362 |
TRPC4 | IP3R2 | Yeast two-hybrid | Human | 615-977 | Yeast | Rat | 2544-2701 | Yeast | 11163362 |
(
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Characterization
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Binding region mapping | Stoichiometry | Affinity (Kd) | Reference | ||||||
TRP channel | Interactor | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | |||
TRPC4 | IP3R2 | Fusion protein-pull down assay | Human | 785-868 | Rat | 2556-2713 | 11163362 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
