TRPC1 / TRPC4

Interaction: TRPC1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / TRPC4Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Screening Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Validation: In vitro validation Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Validation: In vivo validation Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Characterization Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Functional consequence Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b top
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPC1 TRPC4 Inference Prediction 11301024
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Screening Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Validation: In vitro validation Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Validation: In vivo validation Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Characterization Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Functional consequence Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b top
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPC1 TRPC4 Co-immunofluorescence staining BAE-1 16818374
TRPC1 TRPC4 Co-immunofluorescence staining Human glomerular mesangial cell 16418302
TRPC1 TRPC4 Co-immunoprecipitation Rat brain microsome 11301024
TRPC1 TRPC4 Co-immunoprecipitation BAE-1 16818374
TRPC1 TRPC4 Co-immunoprecipitation Human glomerular mesangial cell 19307462
TRPC1 TRPC4 Co-immunoprecipitation HEK293 Human Full-length Mouse Full-length 12032305
TRPC1 TRPC4 Co-immunoprecipitation C57BL/10 mouse muscle cell 19812031
TRPC1 TRPC4 Co-immunoprecipitation Sf9 Human Full-length Bovine Full-length 12377790
TRPC1 TRPC4 Co-immunoprecipitation Rat brain synaptome 12377790
TRPC1 TRPC4 Co-immunoprecipitation Human platelets 16270640
TRPC1 TRPC4 Co-immunoprecipitation Mouse lung endothelium cell 17416589
TRPC1 TRPC4 Co-immunoprecipitation Human glomerular mesangial cell 16418302
TRPC1 TRPC4 Co-immunoprecipitation Mouse lung endothelial cell Mouse Full-length Mouse Full-length 22210847
TRPC1 TRPC4 Co-immunoprecipitation Rat brain microsome 12857742
TRPC1 TRPC4 Co-immunoprecipitation Human platelets 17892531
TRPC1 TRPC4 Fluorescence resonance energy transfer HEK293 Human Full-length Mouse Full-length 12032305
TRPC1 TRPC4 Fluorescence resonance energy transfer Rat pumonary aortic endothelial cell 22534489
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Screening Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Validation: In vitro validation Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Validation: In vivo validation Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Characterization Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b Functional consequence Arrow2 1fb2b8a5ad55723bad55961567d092af30310a7cf44ded6f695fc2aa4753ec2b top
Functional consequence Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPC1 TRPC4 Patch clamp New channel creation 11301024
TRPC1 TRPC4 Patch clamp New channel creation 22144671
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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