TRPC1 / IP3R3

Interaction: TRPC1Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c / IP3R3Detail bc8838fa5bd2464c5553a5a10de82d112f40db7d921ce377f414735e0504230c
Screening Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPC1 IP3R3 Inference Prediction 10766822
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPC1 IP3R3 Co-immunofluorescence staining Human keratinocyte 15654973
TRPC1 IP3R3 Co-immunoprecipitation HEK293 Human Full-length Not used 14505576
TRPC1 IP3R3 Co-immunoprecipitation HSG cell Human Full-length Not used 10766822
TRPC1 IP3R3 Co-immunoprecipitation HSG cell Human Full-length Not used 10980191
TRPC1 IP3R3 Co-immunoprecipitation Human keratinocyte 15654973
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle 893349bafcc528f8346c51dc3420151d67b0126b2c122dd1017121c03fa0f69b
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPC1 IP3R3 Co-immunoprecipitation Human 645-648 Human Not determined 14505576
TRPC1 IP3R3 Co-immunoprecipitation Human 781-789 Human Not determined 19052258
TRPC1 IP3R3 Fusion protein-pull down assay Human 719-751 Human 669-698 11290752
(Link 2bd4d11adb659cddf58197a94e201f0a44c55d8d7cb427c624971b42e122c0a4: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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