TRPC1 / Ƣ-tubulin-5
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Screening
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Experimental screening | Non-experimental screening | Reference | |||||||
TRP channel construct | Interactor source | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
TRPC1 | Ƣ-tubulin-5 | Affinity purification-mass spectrometry | Human | Full-length | Bovine | Retinal | Tissue lysates | 15935109 | |
TRPC1 | Ƣ-tubulin-5 | Yeast two-hybrid | Human | 1-139 | Rat | Brain | cDNA library | 15935109 |
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Validation: In vivo validation
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Assay with endogenous proteins | Assay with overexpressed proteins | Reference | |||||||
Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | ||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | |||
TRPC1 | Ƣ-tubulin-5 | Co-immunofluorescence staining | ARPE-19 | Human | Full-length | Not used | 15935109 | ||
TRPC1 | Ƣ-tubulin-5 | Co-immunoprecipitation | ARPE-19 | Human | Full-length | Not used | 15935109 |
(
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Functional consequence
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TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
TRPC1 | Ƣ-tubulin-5 | Calcium measurement | Inhibition | 15935109 | |||||||
TRPC1 | Ƣ-tubulin-5 | Co-immunofluorescence staining | Increase in plasma membrane level | 15935109 |
(
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
